Bipolar Disorder

A disorder that causes severe and unusually high and low shifts in mood, energy, and activity levels as well as unusual shifts in the ability to carry out day-to-day tasks. (Also known as Manic Depression).

The Balanced Mind Foundation

The The Balanced Mind Foundation (formerly the Children and Adolescent Bipolar Foundation) has resources for families and youths living with bipolar disorder. A section of the site is targeted at educators teaching children with bipolar, and another at teens with the disorder.

Brain & Behavior Research Foundation

The Brain & Behavior Research Foundation’s site answers frequently asked questions about mental illnesses, including bipolar disorder, and discusses research advances in treating and understanding these illnesses.

Depression and Bipolar Disorder

Depression and Bipolar Support Alliance's easy-to-use Web site offers helpful information about mood disorders, support groups, the Association's programs and publications. The site also provides links and resources for further information.

Juvenile Bipolar Research Foundation

The Juvenile Bipolar Research Foundation provides an introduction to bipolar disorder in children, with an overview, frequently asked questions, and suggested resources.

Medline Plus: Bipolar Disorder

This easy-to-use service of the National Library of Medicine provides links to articles, pamphlets, and organizations relating to bipolar disorder.

Mental Health America

Mental Health America provides information about many forms of mental illness, treatment options, medication resources, and ways to get help.

National Alliance on Mental Illness

The National Alliance on Mental Illness Web site houses resources on a host of mental illnesses, such as depression, obsessive-compulsive disorder, and borderline personality disorder. The site also provides information on treatments, support groups, and recovery from mental illness.

Dana Articles

Outside-In Brain Stimulation Shows Promise in the Lab

While deep brain stimulation involves surgery, techniques like transcranial magnetic stimulation and transcranial direct current stimulation are applied from the scalp. Evidence is growing that this outside-in approach also could help improve mental states in people with  schizophrenia who have not found help in other ways.

Lithium to the Rescue

By: Richard S. Jope, Ph.D., and Charles B. Nemeroff, M.D., Ph.D.

(Read Q&A with Richard S. Jope, Ph.D.)
The element lithium is given in capsule form as a mood stabilizer for bipolar disorder and depression. New research, however, reveals its role as a neuroprotector, and suggests that enzymes modulated by lithium could lead to new treatments for Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and other neurodegenerative disorders.

New Clues to the Causes of Bipolar Disorder

Cell and animal models point to abnormalities in two brain areas. 

The Brain Inflamed

Scientists are finding evidence that neuroinflammation can alter mood and cognition, perhaps enough to help cause psychiatric disorders.

The Age Gauge: Older Fathers Having Children

By: Brian M. D’Onofrio, Ph.D., and Paul Lichtenstein, Ph.D.

Is there a link between a father’s age and his child’s vulnerability to psychiatric problems? Two recent studies suggest that children born to middle-aged men are more likely than their older siblings to develop a range of mental difficulties, including bipolar disorder, autism, and schizophrenia.

Psychiatric Drug Development: Diagnosing a Crisis

By: Steven E. Hyman, M.D.

When it comes to funding drug research to treat depression, schizophrenia, anxiety, and other psychiatric disorders, the global pharmaceutical industry prefers to invest its research dollars in cancer, metabolism, autoimmunity, and other disease areas. This comes despite the fact that one in five Americans currently take at least one psychiatric drug and that mental disorders are recognized worldwide.  The author traces the evolution of psychiatric drug development, the reasons for its retreat, and what needs to change to meet the growing demand.