by Roy Hamilton, M.D.
This Phase II study will investigate whether responses by aphasia patients to a form of non-invasive brain stimulation, called transcranial magnetic stimulation, predict their capacity for brain plasticity and recovery of language and motor function....Read more >
by Roy Hamilton, M.D.
Researchers will undertake Phase I of a planned two-phase study to determine whether responses by aphasic stroke patients to a form of non-invasive brain stimulation, called transcranial magnetic stimulation, predict their capacity for brain plastici...Read more >
by Mary-Frances O'Connor, Ph.D.
will use fMRI imaging and other measures in 40 adults whose spouses have
recently passed away to determine whether an oxytocin nose spray reverses signs
of complicated (intense) grief and therefore might lead to an effective
treatment...Read more >
by Brian Berman, M.D., M.S.
will combine PET and fMRI imaging in patients with cervical dystonia to see if
deficits in the neurotransmitter GABA alter the brain’s sensorimotor circuit to
produce the disorder’s characteristic involuntary muscle contractions that
...Read more >
by Scott Slotnick, Ph.D.
techniques in patients and healthy volunteers may identify a biomarker for
diagnosing and assessing treatments for frontal lobe diseases and injuries that
produce visual memory problems, such as Alzheimer’s and other dementing
diseases, a...Read more >
by Robert J. Young, M.D. and Ingo K Mellinghoff, M.D.
Investigators will advance a new MR
spectroscopy (MRS) imaging technique in patients to provide fast and reliable
indicators of deadly brain tumor progression and response to experimental
treatments.Brain tumors may be malignant or
benign. Malign...Read more >
by Conor Liston, M.D., Ph.D.
Researchers will use functional
magnetic resonance imaging (fMRI) techniques in patients with major depressive
disorder (MDD) to try to identify atypical connectivity patterns in the brain that
are biomarkers for diagnosing MDD and for predicting ...Read more >
by Anthony Wagner, Ph.D.
Investigators will use high-powered
MRI imaging in older adults to see whether thinning of a tiny ribbon of tissue
in the brain’s hippocampus is a biomarker for pre-symptomatic Alzheimer’s
disease (AD) and can be used for screening and early detec...Read more >
by Christine DeLorenzo, Ph.D.
soon may be able to use a type of MRI imaging, called diffusion spectrum
imaging, to predict whether an individual patient with depression is likely to
respond to treatment with the class of antidepressants called SSRIs (selective
sero...Read more >
by Corey McMillan, Ph.D.
Investigators will use MRI
imaging techniques to determine which of two proposed pathways young-onset
degenerative diseases use to spread in the brain, and to identify key brain changes
(biomarkers) that can be used to see if experimental therapie...Read more >
by Michael Yartsev, Ph.D.
Vocal learning, or the ability
to hear a sound or word, imitate it, and develop language is often thought of
as a required or necessary human ability, so much so that the lack of
appropriate language acquisition is a hallmark of many neurological ...Read more >
by Ming-Kai Chen, M.D., Ph.D.
a new PET imaging tracer outperform the currently used one in diagnosing Alzheimer’s
disease (AD) and in monitoring its progression?Diagnosing probable AD currently
relies on three major measures. One is whether there is a decrease in glucose
...Read more >
by Michael Zeineh, Ph.D., M.D.
inflammation arising from iron that is converted into an active state in the
brain be the third leg of the Alzheimer’s disease (AD) stool, joining the
abnormal proteins “amyloid” and “tau” as the hallmarks of AD? Stanford
investigators will...Read more >
by Jun Hua, Ph.D.
MRI imaging may be able to pick up
early functional, vascular and metabolic brain changes in people with the
Huntington’s disease gene, potentially providing targets for treating this
devastating disease in its earliest stage. Finding the Huntingt...Read more >
by Jennifer Felger, M.S., Ph.D.
patients being treated for depression continue to lack motivation to engage in
potentially rewarding behaviors, like social interactions, and this problem may
be related to inflammation that impedes communication among reward-related
brain a...Read more >
by Guillermo Horga, M.D., Ph.D.
new molecular MRI imaging technique, called Neuromelanin-sensitive MRI
(NM-MRI), may be able to identify early signs of illness in people who are at a
high risk of developing Parkinson’s disease (PD) or schizophrenia. PD and schizophrenia each ...Read more >
by Mark Dunphy, D.O.
A new non-invasive PET imaging
tracer is showing promise for improving the ability to differentiate indolent
brain tumors from those that are aggressively growing, and for assessing the
aggressive tumor’s response to therapy, faster and more relia...Read more >
by Diego Bohórquez
The Investigators will use two optical
imaging technologies in mice to explore whether a neural circuit that connects
the gut to the brain may be the source of eating and anxiety-like
disorders. The vagus nerve, the longest
nerve in the human bod...Read more >
by Jeffrey M. Yau
will use a novel combination of functional magnetic resonance imaging (fMRI) and
transcranial magnetic stimulation (TMS) to study how the functional connections
between brain regions change in amputees who have lost a lower leg. Thes...Read more >
by Patrick D. Skosnik, Ph.D., and Rajiv Radhakrishnan, M.D.
will use a newly developed positron emission tomography (PET) tracer in individuals
with schizophrenia to examine whether this disorder, and its symptoms and degrees
of severity, are directly associated with decreases in brain synaps...Read more >
by Kayvan Keshari, Ph.D.
new type of MRI imaging that reflects the metabolism of brain tumor cells
versus that of healthy brain cells may serve as an early biomarker of whether a
tumor treatment is working. Aggressive brain tumors, called
gliomas, can be potentially de...Read more >
by Nicola J. Allen, Ph.D.
This cellular imaging study in animal
models will explore whether two genetically determined forms of autism spectrum
disorder (ASD) have similar deleterious alterations in star-shaped cells,
called “astrocytes,” that adversely affect brain develo...Read more >
by Manoj Puthenveedu, M.D., Ph.D.
Investigators will use fluorescence
imaging in a mouse model of chronic pain to identify small molecules that might
potentially manage the pain without the addicting properties and other side
effects of currently used medications.All currently use...Read more >
by Jennifer McNab, Ph.D.
laboratory study in human tissues will determine whether a new imaging
technique called “CLARITY” can enhance image-guided neurosurgery such that
surgeons can optimally place deep brain stimulation (DBS) electrodes to treat
depression, obses...Read more >
by Jared X. Van Snellenberg, Ph.D.
will use a type of fMRI imaging to see whether disconnections in a specific
brain network are a biomarker for identifying clinically high risk
schizophrenia patients who will develop a first episode of psychosis.
Alternatively, thes...Read more >
by Mikhail Shapiro, Ph.D.
Investigators will explore in a
laboratory mouse model of brain injury how the damaging process of inflammation
occurs following injury. Their exploration utilizes a new MRI agent that they
developed and validated through their $100,000 2014 Phase...Read more >