Current Grantees

Using MRI Technology in Zambia and Malawi to Gain Insights into Mechanisms of Brain Injury and Dysfunction in Pediatric Cerebral Malaria

by Michael James Potchen, M.D.

This MRI study in sub-Saharan African children with cerebral malaria will seek to validate initial evidence about how the disease damages the brain and produces severe cognitive and motor disabilities.Nine million children in sub-Saharan Africa devel...
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The Cognitive and Neural Basis of Atypical Social and Moral Cognition in High Functioning Autism

by Liane Young, Ph.D.

This study will use fMRI and behavioral measures to determine whether highly functioning adults with autism spectrum disorders (ASD) have deficits in their abilities to reason about other people’s mental states (beliefs and intentions) and to identif...
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A Causal Neural Network-Level Understanding of Depression and its Treatment through Concurrent TMS and fMRI

by Amit Etkin, M.D., Ph.D.

This study in depressed patients will examine how depression may be produced by malfunctioning interactions of two neural networks and how a non-invasive treatment called repetitive transcranial magnetic stimulation (rTMS) intervenes to improve outco...
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Locus Coeruleus Neuroimaging of Antipsychotic/Modafinil Interactions on Cognition in Schizophrenia

by Michael M. Minzenberg, M.D.

Investigators will use fMRI to assess the extent to which two commonly used antipsychotic drugs interfere with cognitive control functions in patients with schizophrenia. They also will determine how these drugs may limit the effectiveness of medicat...
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A Dual-Modality Molecular Imaging Strategy for Combined Pre- and Intraoperative Imaging of Gliomas

by Moritz Kircher, M.D.,Ph.D.

This study will validate a new MRI imaging technique in an animal model of brain tumor that could enable surgeons to precisely remove all tumor cells to extend survival and possibly save lives.         Patients with deadly brain tumors (glioma) rarel...
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Modulating Motor Behavior by Action Observation and Imitation: Implications for Stroke Rehabilitation

by Lisa Aziz-Zadeh, Ph.D.

Investigators will use MRI and fMRI imaging to examine whether, and how best, the mirror neuron system can be activated following stroke to optimally tailor stroke rehabilitation for individual patients.The human mirror neuron system (MNS) refers to ...
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Brain Imaging of the Glutamatergic System in Depression

by Irina Esterlis, Ph.D.

Investigators will use PET and MRS (magnetic resonance spectroscopy) imaging in patients with depression and healthy volunteers to determine the role that the brain’s glutamate (excitatory) neurotransmitter system plays in depression and its associat...
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New imaging technique may facilitate surgical precision in removing entire brain tumor

by Moritz Kircher, M.D.,Ph.D.

This study will validate a new MRI imaging technique in an animal model of brain tumor that could enable surgeons to precisely remove all tumor cells to extend survival and possibly save lives.         Patients with deadly brain tumors (glioma) rarel...
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