Dr. Zhou earned his Ph.D. degree at Wuhan Institute of Physics, the Chinese Academy of Sciences in 1996. He was trained in the field of magnetic resonance spectroscopy (MRS). He came to the Division of MRI Research, Department of Radiology, Johns Hopkins University, as a Postdoctoral Fellow in 1997. Presently, he is an Assistant Professor of the Johns Hopkins University School of Medicine and an affiliate scientist of the F.M. Kirby Center for Functional Brain Imaging at Kennedy Krieger Institute.
Dr. Zhou’s research focuses on developing new methodologies of magnetic resonance imaging (MRI) and MRS to study brain function and physiology. His previous work about in vivo imaging included absolute quantification of cerebral blood flow, quantification of functional MRI, magnetization transfer mechanism, development of chemical exchange saturation transfer (CEST) technology, brain pH MR imaging, tissue protein MR imaging, and high-resolution diffusion tensor imaging (DTI). A major part of his recent research is in vivo imaging of experimental tumor models and clinical imaging of brain tumor patients using a new MRI technique, the amide proton transfer (APT) imaging. The overall goal is to achieve the MRI contrast at the protein level without exogenous agents and improve the diagnostic capability of MRI and the patient outcomes.
Dr. Zhou has forty-one peer-reviewed papers and one patent. He is a member of International Society of Magnetic Resonance in Medicine (ISMRM), American Association for cancer Research (AACR), and International Society for Cerebral Blood Flow and Metabolism.